Laboratory Equipment & Services Information System by Centralized Laboratory Management Office (CeLMO)

The RKB-3236 Electro Convulsometer is designed to deliver Maximal Electroshock Seizures (MES) via corneal electrodes to laboratory animals, such as rats. This instrument is primarily used to evaluate the anticonvulsant efficacy of pharmacological agents by inducing controlled seizures. The device allows researchers to administer precise electrical stimuli, facilitating the assessment of a compound's ability to prevent or mitigate seizure activity.

• Usage Protocol: Animals are typically restrained, and corneal electrodes are applied with a conductive medium. The device delivers a controlled electrical stimulus to induce seizures, allowing for the assessment of anticonvulsant drug efficacy.
• Maintenance: Regular calibration and maintenance are essential to ensure accurate and consistent results.
• Compliance: Ensure all experiments are conducted following ethical guidelines and institutional regulations for animal research.

• Pharmacological studies: Assessing the anticonvulsant properties of new or existing drugs.
• Neurological research: Investigating the mechanisms underlying seizure activity and epilepsy.
• Toxicological assessments: Evaluating the neurotoxic effects of compounds.
• Educational settings: Demonstrating seizure induction and drug efficacy in laboratory courses.